"This leads to knowledge and ultimately diagnostics, therapeutics and vaccines."
This is the justification for a great deal of biomedical research - the most exalted end-point being a *vaccine*.
However, the most effective way to improve human health has nothing to do with vaccines, drugs, monoclonal antibodies, mRNA and adenovirus vector gene therapies (falsely portrayed as vaccines) or any other medical intervention.
The most effective way to improve human health is to facilitate (by education and support, not mandatory measures, except perhaps in the military) everyone attaining the 50 ng/mL (125 nmol/L = 1 part in 20,000,000 by mass) level of circulating 25-hydroxyvitamin D the immune system needs to function.
This is very simple and of overriding importance for human health.
No matter what food we eat or lifestyle choices we make (except for high levels of ultraviolet B exposure of ideally white skin), the only way we can attain sufficient 25-hydroxyvitamin D is by supplementing proper amounts of vitamin D3 (or, in principle 25-hydroxyvitamin D) according to body weight and obesity status. The one exception is infants who are substantially breast fed by 25-hydroxyvitamin D replete mothers. Such breast milk contains both vitamin D3 and 25-hydroxyvitamin D (Tsugawa et al. 2021 https:// www.mdpi.com/2072-6643/13/2/573), the latter being more important since it is absorbed directly into the infant's circulation, while only (very approximately) 1/4 of ingested vitamin D3 is hydroxylated in the liver to circulating 25-hydroxyvitamin D.
There's far too little vitamin D3 or 25-hydroxyvitamin D in food, fortified or not (often with the less effective vitamin D2) for food to supply more than a small fraction of what we need to attain 50 ng/mL circulating 25-hydroxyvitamin D. There is no such thing as "vitamin D rich food", except in a few cases to boost absolute rock bottom 25-hydroxyvitamin D levels such as 5 ng/mL (which are common in those with dark or black skin, far from the equator) a little, which substantially reduces the risk of children developing rickets. Neither vitamin D3 cholecalciferol nor 25-hydroxyvitamin D calcifediol, made from vitamin D3, primarily in the liver) are hormones.
Please see the research cited and discussed at: https:// vitamindstopscovid.info/00-evi/. This begins with recommendations from New Jersey based Professor of Medicine, Sunil Wimalawansa on the average daily supplemental intake quantities of vitamin D3 which will attain least 50 ng/mL circulating 25-hydroxyvitamin D, over several months, without the need for blood tests or medical monitoring:
70 to 90 IU / kg body weight for those not suffering from obesity (BMI < 30).
100 to 130 IU / kg body weight for obesity I & II (BMI 30 to 39).
140 to 180 IU / kg body weight for obesity III (BMI > 39).
This is because obesity reduces the rate of hydroxylation in the liver and because the resultant 25-hydroxyvitamin D (and probably vitamin D3 itself) is sequestered in the excess adipose tissue: https://5nn.info/ temp/250hd- obesity/.
For 70 kg (154 lb) body weight without obesity, this is about 0.125 milligrams (125 micrograms 5000 IU) a day. This takes several months to attain the desired > 50 ng/mL circulating 25-hydroxyvitamin D. This is 8 or more times what most governments recommend. "5000 IU" a day sounds like a lot, but it is a gram every 22 years - and pharma-grade vitamin D costs about USD$2.50 a gram ex-factory.
These recommendations are included in a recent article with another professor of medicine Scott T. Weiss and professor of pediatrics Bruce W. Hollis: https:// www.mdpi.com/2072-6643/16/22/3969. All three have been researching vitamin D for decades.
Viruses should be researched for numerous purely scientific reasons. They should also be researched for reasons of human health, and that of our companion and agricultural animals. However, the typical justification for this research is that it is an essential step on the paths to post-infection treatments (generally drugs and monoclonal antibodies) and most importantly population wide specific immunity to the viruses in question by way of **vaccines**, as if these are the only or best approaches we have.
This part of the justification is bogus since it ignores the fact that the great majority of humans - and our companion animals (agricultural animals generally get good vitamin D3 or 25-hydroxyvitamin D supplements) - have half or less of the circulating 25-hydroxyvitamin D they need to run their immune systems properly.
In this situation, all arguments about human and non-human animal health should focus first and foremost on getting everyone's immune system functioning properly, which is impossible with less than 50 ng/mL circulating 25-hydroxyvitamin D.
Then, work on therapeutics and in some cases vaccines.
This focus on *vaccines* instead of nutrition (in the case of vitamin D3, since this is the only safe and effective way of attaining 50 ng/mL circulating 25-hydroxyvitamin D, since UV-B skin exposure always damages DNA and so raises the risk of cancer, is not generally available all year round, and would be required in massive amounts for those with dark or black skin) suits the personal interests of virologists, vaccinologists etc. whose income depends entirely on the largely public funded multi-billion dollars per year biomed research industry.
This justification for funding virology etc. does not suit humanity.
The vitamin D3 needed for all humanity to attain 50 ng/mL circulating vitamin D3 all year round is about a tonne a day. At current production costs (UV-B from mercury vapour lamps breaking a carbon ring in 7-dehydrocholesterol derived from wool fat See Industrial Aspects of Vitamin D by Arnold L. Hirsch in 2010: https:// sci-hub.se/10.1016/B978-0-12-381978-9.10006-X ) this would cost about USD$1B a year. This cost would fall with larger scale production and the use of newly developed UV-B LEDs with spectra specifically tuned to the required 293 nm: https://www.houkem.com.cn/high-optical-power-110mw-293nm-295nm-uvb-led-5watt-uv-led-295nm-290nm-293nm-for-vitamin-d.html.
Anyone pushing expensive, multi-year, research projects with the primary end-goal of injecting the whole, or even part of, the population with a vaccine to stimulate necessarily narrow, and likely not very long-lived, immunity to a specific virus or class of viruses, is harming and killing people, because there is no need for more research to greatly improve the health of almost all people.
The biggest problem with vitamin D3 is that it is too simple. Most people can't imagine that all these problems can be substantially resolved by the proper use of a vitamin which has been sitting on supermarket and pharmacy shelves for decades.
This avoidance of attention to genuinely simple solutions to serious and apparently complex problems is what delayed the acceptance of vitamin C to prevent scurvy and hand-washing to prevent the transfer of pathogens for decades.
Please read the research cited and discussed at: https://vitamindstopscovid.info/00-evi/. A fully functional immune system protects against cancer, autism, many chronic conditions such as auto-immune inflammatory diseases, preeclampsia, pre-term birth, sepsis and the later development of autism, ADHD, intellectual disability and schizophrenia in children and against neurodegeneration AKA dementia..
Gain of function research should be regulated to the point of extinction.
But please don't portray virology or any other form of biomedical research as being the most important and urgently needed step governments and/or individuals can take to improve human health.
"This leads to knowledge and ultimately diagnostics, therapeutics and vaccines."
This is the justification for a great deal of biomedical research - the most exalted end-point being a *vaccine*.
However, the most effective way to improve human health has nothing to do with vaccines, drugs, monoclonal antibodies, mRNA and adenovirus vector gene therapies (falsely portrayed as vaccines) or any other medical intervention.
The most effective way to improve human health is to facilitate (by education and support, not mandatory measures, except perhaps in the military) everyone attaining the 50 ng/mL (125 nmol/L = 1 part in 20,000,000 by mass) level of circulating 25-hydroxyvitamin D the immune system needs to function.
This is very simple and of overriding importance for human health.
No matter what food we eat or lifestyle choices we make (except for high levels of ultraviolet B exposure of ideally white skin), the only way we can attain sufficient 25-hydroxyvitamin D is by supplementing proper amounts of vitamin D3 (or, in principle 25-hydroxyvitamin D) according to body weight and obesity status. The one exception is infants who are substantially breast fed by 25-hydroxyvitamin D replete mothers. Such breast milk contains both vitamin D3 and 25-hydroxyvitamin D (Tsugawa et al. 2021 https:// www.mdpi.com/2072-6643/13/2/573), the latter being more important since it is absorbed directly into the infant's circulation, while only (very approximately) 1/4 of ingested vitamin D3 is hydroxylated in the liver to circulating 25-hydroxyvitamin D.
There's far too little vitamin D3 or 25-hydroxyvitamin D in food, fortified or not (often with the less effective vitamin D2) for food to supply more than a small fraction of what we need to attain 50 ng/mL circulating 25-hydroxyvitamin D. There is no such thing as "vitamin D rich food", except in a few cases to boost absolute rock bottom 25-hydroxyvitamin D levels such as 5 ng/mL (which are common in those with dark or black skin, far from the equator) a little, which substantially reduces the risk of children developing rickets. Neither vitamin D3 cholecalciferol nor 25-hydroxyvitamin D calcifediol, made from vitamin D3, primarily in the liver) are hormones.
Please see the research cited and discussed at: https:// vitamindstopscovid.info/00-evi/. This begins with recommendations from New Jersey based Professor of Medicine, Sunil Wimalawansa on the average daily supplemental intake quantities of vitamin D3 which will attain least 50 ng/mL circulating 25-hydroxyvitamin D, over several months, without the need for blood tests or medical monitoring:
70 to 90 IU / kg body weight for those not suffering from obesity (BMI < 30).
100 to 130 IU / kg body weight for obesity I & II (BMI 30 to 39).
140 to 180 IU / kg body weight for obesity III (BMI > 39).
This is because obesity reduces the rate of hydroxylation in the liver and because the resultant 25-hydroxyvitamin D (and probably vitamin D3 itself) is sequestered in the excess adipose tissue: https://5nn.info/ temp/250hd- obesity/.
For 70 kg (154 lb) body weight without obesity, this is about 0.125 milligrams (125 micrograms 5000 IU) a day. This takes several months to attain the desired > 50 ng/mL circulating 25-hydroxyvitamin D. This is 8 or more times what most governments recommend. "5000 IU" a day sounds like a lot, but it is a gram every 22 years - and pharma-grade vitamin D costs about USD$2.50 a gram ex-factory.
These recommendations are included in a recent article with another professor of medicine Scott T. Weiss and professor of pediatrics Bruce W. Hollis: https:// www.mdpi.com/2072-6643/16/22/3969. All three have been researching vitamin D for decades.
Viruses should be researched for numerous purely scientific reasons. They should also be researched for reasons of human health, and that of our companion and agricultural animals. However, the typical justification for this research is that it is an essential step on the paths to post-infection treatments (generally drugs and monoclonal antibodies) and most importantly population wide specific immunity to the viruses in question by way of **vaccines**, as if these are the only or best approaches we have.
This part of the justification is bogus since it ignores the fact that the great majority of humans - and our companion animals (agricultural animals generally get good vitamin D3 or 25-hydroxyvitamin D supplements) - have half or less of the circulating 25-hydroxyvitamin D they need to run their immune systems properly.
In this situation, all arguments about human and non-human animal health should focus first and foremost on getting everyone's immune system functioning properly, which is impossible with less than 50 ng/mL circulating 25-hydroxyvitamin D.
Then, work on therapeutics and in some cases vaccines.
This focus on *vaccines* instead of nutrition (in the case of vitamin D3, since this is the only safe and effective way of attaining 50 ng/mL circulating 25-hydroxyvitamin D, since UV-B skin exposure always damages DNA and so raises the risk of cancer, is not generally available all year round, and would be required in massive amounts for those with dark or black skin) suits the personal interests of virologists, vaccinologists etc. whose income depends entirely on the largely public funded multi-billion dollars per year biomed research industry.
This justification for funding virology etc. does not suit humanity.
The vitamin D3 needed for all humanity to attain 50 ng/mL circulating vitamin D3 all year round is about a tonne a day. At current production costs (UV-B from mercury vapour lamps breaking a carbon ring in 7-dehydrocholesterol derived from wool fat See Industrial Aspects of Vitamin D by Arnold L. Hirsch in 2010: https:// sci-hub.se/10.1016/B978-0-12-381978-9.10006-X ) this would cost about USD$1B a year. This cost would fall with larger scale production and the use of newly developed UV-B LEDs with spectra specifically tuned to the required 293 nm: https://www.houkem.com.cn/high-optical-power-110mw-293nm-295nm-uvb-led-5watt-uv-led-295nm-290nm-293nm-for-vitamin-d.html.
Anyone pushing expensive, multi-year, research projects with the primary end-goal of injecting the whole, or even part of, the population with a vaccine to stimulate necessarily narrow, and likely not very long-lived, immunity to a specific virus or class of viruses, is harming and killing people, because there is no need for more research to greatly improve the health of almost all people.
The biggest problem with vitamin D3 is that it is too simple. Most people can't imagine that all these problems can be substantially resolved by the proper use of a vitamin which has been sitting on supermarket and pharmacy shelves for decades.
This avoidance of attention to genuinely simple solutions to serious and apparently complex problems is what delayed the acceptance of vitamin C to prevent scurvy and hand-washing to prevent the transfer of pathogens for decades.
Please read the research cited and discussed at: https://vitamindstopscovid.info/00-evi/. A fully functional immune system protects against cancer, autism, many chronic conditions such as auto-immune inflammatory diseases, preeclampsia, pre-term birth, sepsis and the later development of autism, ADHD, intellectual disability and schizophrenia in children and against neurodegeneration AKA dementia..
Gain of function research should be regulated to the point of extinction.
But please don't portray virology or any other form of biomedical research as being the most important and urgently needed step governments and/or individuals can take to improve human health.
I am sorry, but this report contains a lot of drivel by the sound of it.
The idea that humans can control a respiratory virus..
Countless harms were done trying to control the population.
People were not informed, but made to feel fear.
People were not allowed to do their own risk assessment.
mRNA products were used without proper long-term safety studies and numerous harms are coming to the fore.
This inquiry is absolutely useless and a waste of time and money.
Unless proper debate is allowed we won’t get any further.
It is truly a scandal of the highest proportions